EXPERT RETINOL RX™ 2% RETI-JECTION™ SERUM

Infused with 2% Retinol RX™ and retinol-infused spicules, this serum delivers professional collagen booster treatment–level efficacy, helping skin appear smoother, firmer, and visibly revitalized.¹

TARGET CONCERNS

Dull Skin · Loss of Firmness · Visible Pores · Fine Lines · Wrinkles

SUITABLE FOR ALL SKIN TYPES
  • Summary

    In a split-face clinical study against professional collagen booster treatments, this formula demonstrated comparable improvements in the appearance of wrinkles, pores, firmness, and radiance. With continued use, skin appears more refined and deep wrinkles look visibly softened.

  • Benefits

    In a split-face clinical study versus professional collagen booster treatments, the serum showed the following improvements after 4 weeks¹:

    WRINKLES -14%
    PORE SIZE -16%
    FIRMNESS +11%
    RADIANCE +38%
    VOLUME +22%

    Dermatologist-Tested

    ¹ Instrumental results from a split-face study in 32 participants; 2 cc collagen booster treatment vs. product used twice daily for 4 weeks. Parameters including firmness, wrinkles, pores, radiance, and volume.

  • Ingredients

    WATER / AQUA / EAU, BUTYLENE GLYCOL, GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, CALCIUM ALUMINUM BOROSILICATE, DIMETHICONE, NIACINAMIDE, BUTYROSPERMUM PARKII (SHEA) BUTTER, PANTHENOL, C14-22 ALCOHOLS, CETEARYL ALCOHOL, TOCOPHEROL, TOCOPHERYL ACETATE, POLYGLYCERYL-3 DISTEARATE, GLYCERYL STEARATE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, PALMITIC ACID, STEARIC ACID, GLYCINE SOJA (SOYBEAN) OIL, C12-20 ALKYL GLUCOSIDE, DIMETHYL ISOSORBIDE, CARBOMER, SODIUM SULFITE, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, ALLANTOIN, GLYCERYL CAPRYLATE, TROMETHAMINE, PENTYLENE GLYCOL, SODIUM METAPHOSPHATE, KOJYL METHYLENEDIOXYCINNAMATE, ETHYLHEXYLGLYCERIN, ADENOSINE, RETINOL, GLYCERYL STEARATE CITRATE, HYDROXYPINACOLONE RETINOATE, BETA-CAROTENE, ACACIA SENEGAL GUM, BHT, PROPYLENE GLYCOL ALGINATE

  • How to use

    - Cleanse skin and apply toner.
    - Apply a full pump to full face at night.
    - May also be used during the day. Always wear sunscreen.

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¹Instrumental results from a split-face study in 32 participants; 2 cc collagen booster treatment vs. product used twice daily for 4 weeks. Parameters including firmness, wrinkles, pores, radiance and volume.

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WHAT IS RETINOL RX™ 2%

RETI-JECTION™ SERUM?





















Retinol RX™ Reti-jection Serum is engineered to deliver collagen booster treatment–level results, demonstrated in a split-face clinical study¹.


This efficacy is powered by the synergy of IOPE’s proprietary retinol formulation and micro needle–like spicule technology, designed to support enhanced absorption and optimized delivery.


Ideal for those who have not seen visible results from retinol, or who are concerned with fine lines, loss of firmness, and enlarged pores.














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INNOVATIVE DELIVERY TECHNOLOGY POWERED BY 3 MILLION

RETINOL-INFUSED SPICULES²



















Spicules are ultra-fine, microneedle-like particles that enhance absorption and refine the skin surface, creating a mild tingling sensation.


IOPE advances this technology by infusing retinol directly into the spicules, enabling more efficient delivery. In a clinical study, the serum demonstrated 46% enhanced absorption compared to spicule-free formulations.


Despite its high-performance efficacy, the sensory remains gentle. IOPE softened and polished the edges of the spicules, reducing irritation by 80%³ while enhancing skin comfort for a smoother application experience.





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MEDICALLY INSPIRED

IOPE's PROPRIETARY ADVANCED FORMULATION, RETINOL RX™


















Backed by 30 years of retinol research, IOPE has developed ways to enhance retinol efficacy while helping reduce irritation.


Traditional retinol typically undergoes several conversion steps before becoming active in the skin. IOPE’s Retinol RX™ is designed to become active without additional conversion, helping maintain consistent efficacy while improving skin tolerability.


This serum features a 2% concentration of Retinol RX™, enhanced with IOPE’s spicule technology to support optimized delivery. With continued use, wrinkles appear reduced and deeper signs of aging look visibly improved.




VISIBLE IMPROVEMENTS IN

LINES & WRINKLES

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IOPE,International
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AFTER

4 WEEKS⁴

agree skin felt firm

100
%

agree pores appeared tighter

96
%

agree fine lines looked reduced

93
%
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HOW TO USE


STEP 1

Cleanse skin and apply toner.


STEP 2

Apply a full pump to full face at night.


STEP 3

Always wear sunscreen during the day.


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PROFESSIONAL-LEVEL

ANTI-AGING RETINOL ROUTINE



















STEP 1

Retinol RX™ 1% Serum

Low-irritation daytime firming care


STEP 2

Retinol RX™ 2% Serum

Intensive nighttime care for collagen booster efficacy


STEP 3

Retinol Hydrogel Mask

Lock-in Booster Mask for amplified retinol synergy




¹ Instrumental results from a split-face study in 32 participants; 2 cc collagen booster treatment

vs. product used twice daily for 4 weeks. Parameters including firmness, wrinkles, pores,

radiance, and volume.

² Average number of spicule based on 30 mL / 1.01 fl. oz. (full-sized product).

³ Sensory evaluation (n=31): 0.5% Reti-jection spicule cream vs. 0.5% hydrolyzed sponge spicule cream, stinging and burning assessed over 9 minutes.

⁴ Self-assessment from clinical, 32 participants, used 2x daily for 4 weeks.